Pharmacology RSM

BIOL20932 Pharmacology RSM 10 Semester 2 Undergraduate Level 2 Harry Potter Unit coordinator School of Biological Sciences 1 FHEQ level (Framework for Higher Education Qualifications) ' Middle part of Bachelors ' European Credit Transfer & Accumulation System Rating : 5.0 This Research Skills Module is designed to develop your experimental design, report writing and practical skills. You will investigate a range of topics including drug toxicity testing, anaesthesia, computer based molecular modelling and the ethical issues surrounding drug testing on human volunteers. This Research Skills Module is designed to develop your experimental design, report writing and practical skills. You will investigate a range of topics including drug toxicity testing, anaesthesia, computer based molecular modelling and the ethical issues surrounding drug testing on human volunteers. Working as a team you will research and present the mechanisms and effects of a clinically important drug. To provide practical experience of research methods used in the discovery of drugs, from initial ideas through to full clinical use in man. <ul> <li> Understand methods used in drug discovery and development</li> <li> Improve technical skills</li> <li> Find and understand information</li> <li> Analyse complex data sets</li> <li> Write scientific reports</li> </ul> Analytical skills Extensive data handling and analysis required to write up practicals Group/team working All practicals are done in groups; students also complete a group-based results report Problem solving Extensive data handling and analysis required to write up practicals Research Research on muscarinic receptors as drug targets is required for the full practical report.Group based oral and written presentations on novel drugs Written communication Full Group based oral and written presentations on novel drugs, practical report written in the style of a research papers. Other Practical lab skills. Discipline specific laboratory skills, knowledge of drug discovery strategies May include “wet lab” versions or simulations ofRadioligand binding assay: competition and saturation binding assays Computer methods for drug discovery: prediction of drug potency using molecular modelling software. Practical data analysis: graphing and analysing experimental data using GraphPad Prism software. Schild analysis: students will study the interaction of methacholine and atropine analogues in rat ileum. Human volunteer practicals e.g. paracetamol metabolism Animal tissue practicals such as a dissection<ul></ul> 0 Other 10% 3 Report 40% 6 Project output (not diss/n) 30% 9 Set exercise 20% <ul> <li>Pre-RSM e-assessments mcqs and short note questions (10%)</li> <li>Short note questions (30%)</li> <li>Full practical write-up (40%)</li> <li>Group based results report (incl peer assessment) 20%)</li></ul> RSM Attendance guidelines.Students are expected to attend all scheduled RSM sessions on time (N.B. Health and safety information will be delivered at the start of practical sessions, and students who are not present at the start may be asked to leave the lab). Students who arrive late will be marked as absent for that session. Failure to attend a session (an unauthorised absence) will result in a 10% (i.e. 10 mark) penalty being applied to the overall RSM mark (i.e. a student obtaining a mark of 65% overall will instead receive a mark of 55%). Furthermore, any students who miss a practical session will not receive a mark for any associated post-lab assessment (N.B. this mark will be removed before calculating the average post-lab mark to avoid a student being penalised twice).Further absences will result in further penalties (i.e. 2 absences = a penalty of 20% (as described above)).Due to the use of animal tissues, students are also required to complete Health Screening by the University Occupational Health Service. Not completing screening will result in exclusion and unauthorised absence from the relevant practicals and mark penalties as detailed above. Feedback will be provided via annotated practical write-ups and verbal advice on practical techniques during classes. BIOL10822 Drugs: From Molecules to Man Pre-Requisite Compulsory BIOL21302 Clinical Drug Development Co-Requisite Compulsory BIOL20932 Pre & Co-requisite are BIOL10822 & BIOL21302BIOL20932 Co-requisite is BIOL21302 BSc(Hons) Biology BSc(Hons) Biology Second Year Optional BSc (Hons) Biology with IE/PE BSc (Hons) Biology with IE/PE Second Year Optional BSc(Hons) Biology w Mod Lang BSc(Hons) Biology w Mod Lang Second Year Optional BSc(Hons) Biology w Mod Lang BSc(Hons) Biology w ML (Asian) Second Year Optional BSc (Hons) Biomed Sci w IE/PE BSc (Hons) Biomed Sci w IE/PE Second Year Optional BSc(Hons) Biomedical Sciences BSc(Hons) Biomedical Sciences Second Year Optional BSc (Hons) Pharm & Phys IE/PE BSc (Hons) Pharm & Phys IE/PE Second Year Optional BSc(Hons) Pharmacol & Physiol BSc(Hons) Pharmacol & Physiol Second Year Optional BSc (Hons) Pharmacology IE/PE BSc (Hons) Pharmacology IE/PE Second Year Mandatory BSc(Hons) Pharmacol w Mod Lang BSc(Hons) Pharmacol w Mod Lang Second Year Mandatory BSc(Hons) Pharmacol w Mod Lang BSc(Hons) Pharm w ML (Asian) Second Year Mandatory BSc(Hons) Pharmacology BSc(Hons) Pharmacology Second Year Mandatory BSc(Hons) Biomed Sci w Mod Lan BSc(Hons) Biomed Sci w Mod Lan Second Year Optional BSc(Hons) Biomed Sci w Mod Lan BSc(Hons) Bio Sci w ML (Asian) Second Year Optional MSci Biology MSci Biology Second Year Optional MSci Biomedical Sciences MSci Biomedical Sciences Second Year Optional MSci Pharmacology MSci Pharmacology Second Year Mandatory BSc(Hons) Biol with Entrepren BSc(Hons) Biol with Entrepren Second Year Optional BSc(Hons) Biomed Sci W Entrepr BSc(Hons) Biomed Sci w Entre Second Year Optional BSc(Hons) Pharma w Entre BSc(Hons) Pharma w Entre Second Year Mandatory N Practical classes & workshops 43 0 57