Clinical Sciences RSM

BIOL20902 Clinical Sciences RSM 10 Semester 2 Undergraduate Level 2 Michelle Keown Unit coordinator School of Biological Sciences 1 FHEQ level (Framework for Higher Education Qualifications) ' Middle part of Bachelors ' European Credit Transfer & Accumulation System Rating : 5.0 This Research Skills Module is designed to develop your experimental design, report writing and practical skills. In a series of practical sessions, you will develop an understanding of the principles underpinning common clinical diagnostic/research techniques in clinical biochemistry, haematology, pathology and microbiology. Topics include; investigating a sample of food implicated in food poisoning, diagnosis of a tumour tissue and investigating the safety and efficacy of new anticoagulant drugs using plasma samples. This Research Skills Module is designed to develop your experimental design, report writing and practical skills. In a series of practical sessions, you will develop an understanding of the principles underpinning common clinical diagnostic/research techniques in clinical biochemistry, haematology, pathology and microbiology. Topics include; investigating a sample of food implicated in food poisoning, diagnosis of a tumour tissue and investigating the safety and efficacy of new anticoagulant drugs using plasma samples. <ul> <li>To introduce students to theory and practice of a selection of commonly used techniques used in both clinical and research laboratories</li> <li>To provide training in experimental design and critical interpretation of data</li> <li>To develop practical skills and team working ability</li></ul> Students will:<ul> <li>Develop an understanding of the principles underpinning common clinical diagnostic/research techniques in clinical biochemistry, haematology, pathology and microbiology as well as their respective applications and uses.</li> <li>Know how to perform various clinical laboratory research techniques in the aforementioned areas and recognise the need for good experimental design and laboratory practice.</li> <li>Collect, analyse and present data in a format for publication.</li></ul> Analytical skills All weeks will involve analysis of data/findings and will include manipulation of data and presentation of this information in many formats. Group/team working Most experiments will involve an element of small group working/team work. Innovation/creativity Many experiments will include an element of innovation where students will be expected to design and plan their actual experiment from start to finish. For e.g. in Pathology and Haematology weeks. Leadership Opportunities for leadership role(s) in various experiments during the 4 weeks. Project management There will be opportunities for project management in various experiments. Oral communication Many opportunities to ask and answer questions during all sessions on a one-to-one basis and in small groups. Problem solving This will be part of all practical experiments in this RSM and also will be incorporated in case studies on some weeks. Research All weeks will included a research element be it through wetlab experiments or dry 'case study' scenarios. Written communication Online assessments associated with various practicals/experiments and extended practical write-up (scientific paper style). During the RSM students will gain experience in 4 different clinical laboratory settings; Clinical Microbiology, Biochemistry, Pathology and Haematology.Clinical Microbiology will include modelling of a synthetic epidemic as well as identification of bacteria causing infections using selective media, microscopy, biochemical tests and 16srRNA sequencing.Clinical Biochemistry will look at analysis of blood & urine samples where possible from clinical research scenarios including diabetes and chronic kidney disease. Techniques will include urinalysis, microscopy, urinary drug metabolite testing.Preparation of experimental solutions, tissue section, histology, immunohistochemistry, diagnosis of tumour tissue as well as data analysis will form the basis of clinical pathology.For haematology there will be an investigation of the safety and efficacy of new anticoagulant treatments. Students will generate a test hypothesis and design appropriate experiments including selection of appropriate methodologies, data analysis and interpretation. 0 Other 50% 2 Written assignment (inc essay) 45% 9 Set exercise 5% Continuous assessment of each week by short answer questions including data analysis and interpretation (45%) Extended write-up in style of a research paper (50%) Short online test: good laboratory practice (5%)RSM Attendance guidelines. Students are expected to attend all scheduled RSM sessions on time (N.B. Health and safety information will be delivered at the start of practical sessions, and students who are not present at the start may be asked to leave the lab). Students who arrive late will be marked as absent for that session. Failure to attend a session (an unauthorised absence) will result in a 10% (i.e. 10 mark) penalty being applied to the overall RSM mark (i.e. a student obtaining a mark of 65% overall will instead receive a mark of 55%). Further absences will result in further penalties (i.e. 2 absences = a penalty of 20% (as described above)). <ul> <li>During the practical sessions there will be many opportunities for immediate feedback from staff and demonstrators</li> <li>Individual feedback on assessed work</li></ul> BIOL10811 Body Systems Pre-Requisite Recommended This unit may be selected by Biomedical Sciences or Biology students. BSc(Hons) Biology BSc(Hons) Biology Second Year Optional BSc (Hons) Biology with IE/PE BSc (Hons) Biology with IE/PE Second Year Optional BSc(Hons) Biology w Mod Lang BSc(Hons) Biology w Mod Lang Second Year Optional BSc(Hons) Biology w Mod Lang BSc(Hons) Biology w ML (Asian) Second Year Optional BSc (Hons) Biomed Sci w IE/PE BSc (Hons) Biomed Sci w IE/PE Second Year Optional BSc(Hons) Biomedical Sciences BSc(Hons) Biomedical Sciences Second Year Optional BSc(Hons) Biomed Sci w Mod Lan BSc(Hons) Biomed Sci w Mod Lan Second Year Optional BSc(Hons) Biomed Sci w Mod Lan BSc(Hons) Bio Sci w ML (Asian) Second Year Optional MSci Biology MSci Biology Second Year Optional MSci Biomedical Sciences MSci Biomedical Sciences Second Year Optional BSc(Hons) Biol with Entrepren BSc(Hons) Biol with Entrepren Second Year Optional BSc(Hons) Biomed Sci W Entrepr BSc(Hons) Biomed Sci w Entre Second Year Optional N All recommended reading will be made available through Blackboard and a printed manual will be distributed to students on a weekly basis which contains background information and a description of the relevant practical work. Practical classes & workshops 72 0 28