Personalised Learning Unit 1-Industrial Placements

CHEM32111 Personalised Learning Unit 1-Industrial Placements 10 Semester 1 Undergraduate Level 3 David Collison Unit coordinator Department of Chemistry 1 FHEQ level (Framework for Higher Education Qualifications) ' Last part of a Bachelors ' European Credit Transfer & Accumulation System Rating : 5.0 This personalised learning unit is for students away on industrial placement.  <p style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(81, 81, 81);font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:-webkit-left;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">The unit aims to:<p style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(81, 81, 81);font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:-webkit-left;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">The over-arching aims of these modules is to prepare students for a professional or research career in Chemistry by expanding core chemistry knowledge into advanced, research-based topics to provide a wider and deeper understanding of particular areas of chemistry.<p style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(81, 81, 81);font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:-webkit-left;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">The key aims of each of the segments are:<p style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(81, 81, 81);font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:-webkit-left;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">Solid-State Computational Chemistry – to introduce and understand computational techniques for studying structure and bonding in crystalline inorganic compounds.<p style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(81, 81, 81);font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:-webkit-left;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">Metals in Biology – to introduce students to the contribution of metal ions in biology and medicine, providing a context for coordination chemistry beyond the laboratory and textbooks<p style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(81, 81, 81);font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:-webkit-left;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">Biocatalysis by Organic Cofactors – to introduce students to organic (bio)chemistry as catalysed by organic cofactors, exploring the link between the catalyst structure and biological function.<p style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(81, 81, 81);font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align: <p style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(81, 81, 81);font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:-webkit-left;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">Solid-State Computational Chemistry<ul><li>ILO1 - Explain the quantum mechanical basis of electronic structure theory as used in modern computational chemistry</li><li>ILO2 – Describe the electronic structure of solids and explain resultant properties of inorganic materials</li><li>ILO3 – Describe the origins and applications of Hartree-Fock theory and density functional theory</li><li>ILO4 – Discuss application of computational chemistry in inorganic chemistry research</li></ul><p style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(81, 81, 81);font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:-webkit-left;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">Metals in Biology <ul><li>ILO1 - Apply prior knowledge of coordination chemistry to metal sites within biological environments </li><li>ILO2 - Describe key biological roles of metal ions in the body</li><li>ILO3 - Illustrate the effects of elements not normally found in Nature when taken into the body</li><li>ILO4 - Show how small structural changes at a metal centre can orchestrate molecular signal transduction</li><li>ILO5 - Evaluate the coordination sphere of metal ions within biological molecules and predict how this affects the properties of the biomolecule</li><li>ILO6 - Design experiments and small molecules capable of informing our understanding of biological processes</li></ul><p style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(81, 81, 81);font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:-webkit-left;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">Biocatalysis by organic cofactors<ul><li>ILO1 - Describe the role of organic cofactors in biocatalysis and identify various cofactors based on their structure</li><li>ILO2 - Explain how the structure of organic cofactors is tailored to the corresponding biocatalytic function</li><li>ILO3 - Evaluate the effect(s) on protein binding and/or biocatalytic function of cofactor structure modifications</li><li>ILO4 - Rationalise the component steps in mechanisms of covalent catalysis by PLP/TPP and highlight aspects under enzyme control</li><li>ILO5 - Rationalise the components steps in redox mechanisms catalysed by FAD/FMN/NAD(P)H and highlight aspects under enzyme control</li></ul><p style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(81, 81, 81);font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:-webkit-left;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">Advanced Separations<ul><li>ILO1 - Reflect on the challenges in determining complex multi-component systems</li><li>ILO2 - Describe the principles of advanced separation science and mass spectrometry techniques to obtain experimental measurements in t <p style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(81, 81, 81);font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:-webkit-left;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">On successful completion of the course students should be able to:  <ul><li>Extend ideas from core chemistry units from years 1 and 2 to advanced topics.</li><li>Describe and explain the concepts and application of each topic.</li><li>Apply the concepts of the topic and extend these to synthesise new solutions.</li><li>Rationalise and interpret data from each topic.</li><li>Propose, and illustrate, outcomes of unseen extensions to the topic material. </li></ul> <span style="-webkit-text-stroke-width:0px;display:inline !important;float:none;font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:-webkit-left;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">Problem solving, analytical skills, time management. <p style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(81, 81, 81);font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:-webkit-left;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">Solid-State Computational Chemistry (H. W.T. Morgan)<ul><li>Electronic structure theory of solids – fundamentals and real material examples</li><li>Hartree-Fock theory and density functional theory</li><li>Computational methods for studying properties and reactions of solids.</li></ul><p style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(81, 81, 81);font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:-webkit-left;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">Metals in Biology (L.S. Natrajan)<ul><li>Bio-basics; the role of metal ions in biology and their uptake in mammalian cells</li><li>Divalent Metal Transporter; Fe in Mammals; Fe in Bacteria; and Biomineralisation</li><li>Catalytic; Structural; and Mobile Zinc  </li><li>Anticancer treatment and Metal Toxicity</li></ul><p style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(81, 81, 81);font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:-webkit-left;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">Biocatalysis by Organic Cofactors (D. Leys)<ul><li>Definition and overview of organic cofactors</li><li>Covalent catalysis by PLP/TPP</li><li>Redox catalysis by FAD/FMN/NAD(P)H</li><li>Molecular machines illustrated by pyruvate decarboxylase</li></ul><p style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(81, 81, 81);font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:-webkit-left;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">Advanced Separations (N.P. Lockyer)<ul><li>Optimisation of column chromatography</li><li>Ion Mobility (Mass) Spectrometry</li><li>Advanced Mass Spectrometry techniques and Instrumentation</li></ul><p style="-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(81, 81, 81);font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:-webkit-left;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">Electronic Structure Theory (P.L.A. Popelier)<ul><li>Explicit Hamiltonians</li><li>Variation 0% <span style="-webkit-text-stroke-width:0px;display:inline !important;float:none;font-family:Arial, sans-serif;font-size:12px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:-webkit-left;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;">Pre-requisite units: All Year 1 and Year 2 Core modules  N 0 Placement 100 0 This unit is designed for students away on industrial placement year 3.