MEDN61850
Histocompatibility
15
Semester 1
Postgraduate Taught
Level 6
Amanda Robson
Unit coordinator
Institute of Inflammation and Repair
1
FHEQ level (Framework for Higher Education Qualifications) ' Masters/Integrated Masters P4 '
European Credit Transfer & Accumulation System Rating : 7.5
<div>
<p>The overall aim of this unit is to provide students with knowledge and understanding of the scientific basis of organ transplantation. They will understand the clinical preparation of patients for organ transplantation and the principles and practice of immunogenetics. They will become familiar with methods that support transplantation and gain experience of the interpretation of patient results in a variety of clinical settings. In addition, the unit will provide students with a basic knowledge and understanding of the use of biostatics for the interrogation of laboratory data</p></div>
<p> </p>
<div>
<p>The overall aim of this unit is to provide students with knowledge and understanding of the scientific basis of organ transplantation. They will understand the clinical preparation of patients for organ transplantation and the principles and practice of immunogenetics. They will become familiar with methods that support transplantation and gain experience of the interpretation of patient results in a variety of clinical settings. In addition, the unit will provide students with a basic knowledge and understanding of the use of biostatics for the interrogation of laboratory data</p></div>
<p> </p>
<div>
<p><em>The unit aims to:</em></p><p>- provide students with a knowledge and understanding of the biological basis of organ transplantation.</p><p>- equip students with a understanding of the principles and practice of immunogenetics in relation to organ transplantation</p><p>- provide students with a understanding the role of the histocompatibility and immunogenetics laboratory in the pre transplant work up and post transplant management of patients, and the knowledge and skills to interpret and analyse the scientific data obtained by the laboratory.</p><p>- provide students with an introduction to biostatistics</p></div>
<p> </p>
<ul>
<li>
Understand the immunological barriers to solid organ and haemopoeitic stem cell transplantation.</li>
<li>
Understand the mechanisms of graft rejection and the relevance of pre- sensitisation.</li>
<li>
Understand the mechanisms of current immunosuppressive therapies in the control of graft rejection.</li>
<li>
Understand the role of the histocompatibility and immunogenetics laboratory in the pre transplant work up and post transplant management of patients.</li>
<li>
Describe the design, operation and performance of appropriate laboratory tests in support of: 1) HLA antibody identification and definition, HLA typing and data analysis and 2) cross matching for solid organ transplantation.</li>
</ul>
<ul>
<li>
Understand the immunological barriers to solid organ and haemopoeitic stem cell transplantation.</li>
<li>
Understand the mechanisms of graft rejection and the relevance of pre- sensitisation.</li>
<li>
Understand the mechanisms of current immunosuppressive therapies in the control of graft rejection.</li>
<li>
Understand the role of the histocompatibility and immunogenetics laboratory in the pre transplant work up and post transplant management of patients.</li>
<li>
Describe the design, operation and performance of appropriate laboratory tests in support of: 1) HLA antibody identification and definition, HLA typing and data analysis and 2) cross matching for solid organ transplantation.</li>
</ul>
<ul>
<li>
Present information clearly in the form of verbal and written reports. </li>
<li>
Communicate complex ideas and arguments in a clear and concise and effective manner.</li>
<li>
Work effectively as an individual or part of a team. </li>
<li>
Use conventional and electronic resources to collect, select and organise complex scientific information</li>
</ul>
<ul>
<li>
Effectively utilise a range of information sources including information technology / health informatics. </li>
<li>
Demonstrate capacity for self-learning and independent thinking and to utilise problem solving skills. </li>
<li>
Demonstrate effective communication skills (verbal and written). </li>
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Be able to set priorities and link these with effective time management. </li>
<li>
Critically evaluate their personal performance both as an individual and within a team. </li>
<li>
Demonstrate skills in working collegiately and effectively with others</li>
</ul>
<div>
<p>This unit employs a range of teaching and learning approaches including: lecturers, tutorials, case studies/presentations, problem-based learning. Initially the involvement of e-learning will be restricted to online formative assessments. However, the goal is to generate on-line teaching material to support the face to face teaching. The online material will support the acquisition of knowledge and understanding by promoting problem-based learning through interactive material, exercises and self assessment tools.</p></div>
<p> </p>
1
Written exam
50%
2
Written assignment (inc essay)
50%
<p style="margin-left: 11.4pt">Marks will be provided online within 3/4 weeks of assessment deadline</p>
MSc Clinical Science
MSc Clin Sci - Histo & Immuno
PGDT Taught Component
Mandatory
N
0
0
150